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PU-H71 HCl

CAS No. 2095432-24-7

PU-H71 HCl ( —— )

产品货号. M36291 CAS No. 2095432-24-7

PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT. PU-H71 HCL shows antitumor activity in many preclinical models of malignancy. PU-H71 HCL has an inhibitory effect on the protein expression levels of Rad51 and Ku70, which may be associated with the double chain break repair in the homologous recombination pathway and non-homologous end-joining pathway.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥2519 有现货
5MG ¥3472 有现货
10MG ¥5136 有现货
25MG ¥7718 有现货
50MG ¥10635 有现货
100MG ¥14000 有现货
500MG ¥28152 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    PU-H71 HCl
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT. PU-H71 HCL shows antitumor activity in many preclinical models of malignancy. PU-H71 HCL has an inhibitory effect on the protein expression levels of Rad51 and Ku70, which may be associated with the double chain break repair in the homologous recombination pathway and non-homologous end-joining pathway.
  • 产品描述
    PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT. PU-H71 HCL shows antitumor activity in many preclinical models of malignancy. PU-H71 HCL has an inhibitory effect on the protein expression levels of Rad51 and Ku70, which may be associated with the double chain break repair in the homologous recombination pathway and non-homologous end-joining pathway.
  • 体外实验
    ——
  • 体内实验
    ——
  • 同义词
    ——
  • 通路
    Cytoskeleton/Cell Adhesion Molecules
  • 靶点
    HSP
  • 受体
    HSP | DNA/RNA Synthesis
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    2095432-24-7
  • 分子量
    548.83
  • 分子式
    C18H22ClIN6O2S
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    Cl.IC=1C=C2OCOC2=CC1SC3=NC=4C(=NC=NC4N3CCCNC(C)C)N
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

产品手册
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